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Date Name Thumbnail Size User Description Versions
06:24, 5 June 2007 MSE.png (file) 17 KB AndiVanessaBaramuli   1
06:49, 5 June 2007 Pprofunc superfamily.JPG (file) 127 KB TimmHaack   1
06:57, 5 June 2007 LOC144557(with ligand bound).doc (file) 128 KB SauravMalhotra   1
11:09, 5 June 2007 Binding sites.JPG (file) 124 KB VernChiew   1
12:36, 5 June 2007 Surface charge.JPG (file) 69 KB VernChiew   1
13:05, 5 June 2007 Conserved.JPG (file) 40 KB Heenwai   1
13:09, 5 June 2007 Surface properties.JPG (file) 35 KB Heenwai   1
13:15, 5 June 2007 Po4 ligand.JPG (file) 72 KB Heenwai   1
13:17, 5 June 2007 Edo4 ligand.JPG (file) 64 KB Heenwai   1
13:19, 5 June 2007 Clefts.JPG (file) 132 KB Heenwai   1
13:20, 5 June 2007 2gfh and 2hx1.JPG (file) 43 KB Heenwai   1
13:22, 5 June 2007 2gfh and 2ho4.JPG (file) 56 KB Heenwai   1
13:24, 5 June 2007 2gfh and 1fez.JPG (file) 42 KB Heenwai   1
13:27, 5 June 2007 Ligand.JPG (file) 58 KB VernChiew   1
17:09, 6 June 2007 COASYStructconoriginal.wmv (file) 1.91 MB BenLeahy COASY structural conservation structure alignment movie 1
00:59, 8 June 2007 Properties and Functions of GAF Domains in Cyclic Nucleotide Phosphodiesterases and Other Proteins.pdf (file) 831 KB SamDai   1
01:01, 8 June 2007 Olfactory cGMP PDE2.PDF (file) 1.03 MB SamDai   1
07:51, 8 June 2007 Treetrans.JPG (file) 15 KB Wilsonchang   1
07:53, 8 June 2007 Treetrans.jpg (file) 15 KB Wilsonchang   1
10:42, 8 June 2007 Final CoA synthesis pathway 2.gif (file) 73 KB HayleyThomas CoA synthesis pathway. Adapted from: Daugherty, M., Polanuyer, B., Farrel, M., Scholle, M., Athanasios, L., de Crecy-Lagard, V. et. al. (2002). Complete Reconstitution of the Human Coenzyme A Biosynthetic Pathway via Comparative Genomics. J Biol Chem , 27 1
23:42, 8 June 2007 CoAsy.jpg (file) 27 KB HayleyThomas Structure of CoAsy chain A from PDB file. (RCSB. (2007, 5 29). RCSB PDB : Structure Explorer. Retrieved 6 9, 2007, from RCSB Protein Data Bank: http://www.pdb.org/pdb/explore.do?structureId=2F6R 1
00:39, 9 June 2007 Domains 2F6r.jpg (file) 30 KB HayleyThomas PPAT and DPCK domains of CoA synthase 1
00:41, 9 June 2007 ACO and DephosphoCoA (fig in report).gif (file) 12 KB HayleyThomas Dephospho-CoA structure reproduced from: Daugherty, M., Polanuyer, B., Farrel, M., Scholle, M., Athanasios, L., de Crecy-Lagard, V. et. al. (2002). Complete Reconstitution of the Human Coenzyme A Biosynthetic Pathway via Comparative Genomics. J Biol Chem 1
03:48, 9 June 2007 COASYSeqcongif.gif (file) 1.98 MB BenLeahy Ribbon representation of Mus. Muculus Coenzyme A Synthase (PDB) with conservation of sequence positions marked for structurally related proteins. Note strong conservation around ATP binding site on P-Loop (residues 70-75). 2
04:01, 9 June 2007 COASYStructcongif.gif (file) 1.91 MB BenLeahy Ribbon representation of Mus. Muculus Coenzyme A Synthase (PDB) with conservation of structural features marked for structurally related proteins. Note P-Loop conservation (residues 65-85). 2
04:55, 9 June 2007 Image001.png (file) 144 KB TimmHaack   1
05:07, 9 June 2007 Image002.jpg (file) 18 KB TimmHaack   1
05:08, 9 June 2007 Image003.png (file) 127 KB TimmHaack   1
05:13, 9 June 2007 Image005.png (file) 172 KB TimmHaack   1
05:17, 9 June 2007 Image007.png (file) 5 KB TimmHaack   1
05:38, 9 June 2007 Image009.png (file) 55 KB TimmHaack   1
05:40, 9 June 2007 Image011.png (file) 55 KB TimmHaack   1
06:00, 9 June 2007 Surface charges 1zkd.PNG (file) 418 KB TimmHaack   1
06:11, 9 June 2007 Image021.png (file) 45 KB TimmHaack   1
06:21, 9 June 2007 ClustalX omit.jpg (file) 339 KB HareshMohanan   1
06:44, 9 June 2007 Tree wit bootstrap.JPG (file) 107 KB HareshMohanan   1
09:12, 9 June 2007 Sequence & secondary structure PDB.bmp (file) 906 KB MelissaBrown   1
12:39, 9 June 2007 Protein2.JPG (file) 79 KB JohnTsai Example of catalytic mechanism of ATPase and phosphatase activity of HAD superfamily protein processess. 1
14:19, 9 June 2007 COASYApbs mapped binding cradle shown with aligned DPCK IJJV and associated ATP ligand biniding.jpg (file) 63 KB BenLeahy Surface map of Mus musculus Coenzyme A Synthase with electrostatic charge indicated, ATP ligand is included at P-Loop bind site of DPCK domain and ACO at the proposed Dephospho Coenzyme E Kinase cleft. 1
16:39, 9 June 2007 Secondary structure comparsion.jpg (file) 70 KB BenLeahy Structural comparison of Dephospho-COA Kinase (IJJV) and Bifunctional coenzyme A synthase from Mus musculus (2F6R) with bound ATP. 1
16:49, 9 June 2007 COASYBfactor.jpg (file) 47 KB BenLeahy Coenzyme A Synthase Mus musculus surface structure marked by B-Factor. 1
16:51, 9 June 2007 COASYSecondary structure comparsion.jpg (file) 70 KB BenLeahy Structural comparison of Dephospho-COA Kinase (IJJV) and Bifunctional coenzyme A synthase from Mus musculus (2F6R) with bound ATP. 1
17:43, 9 June 2007 Ligandbindingsitepredictioni2.png (file) 31 KB AndiVanessaBaramuli   1
18:01, 9 June 2007 COASYHydro.jpg (file) 55 KB BenLeahy Sequence alignment of N domain (first 30 residues) of Coenzyme A Synthase proteins (bottom) with hydrophobic residues shaded. The hydrophobicity profile (top) of Coenzyme A Synthase was generated by TMpred program (Hofmann & Stoffel, 1993). A Modular repr 1
18:03, 9 June 2007 COASYHydro2.jpg (file) 39 KB BenLeahy Coenzyme A Synthase Mus. musculus ribbon structure showing hydrophobic regions. 1
19:08, 9 June 2007 COASYCleft table.jpg (file) 88 KB BenLeahy Informational table for Cleft locations of CoAsy 2f6r 1
19:19, 9 June 2007 COASYClefts.jpg (file) 129 KB BenLeahy Binding cleft locations of CoAsy 2f6r 2
23:40, 9 June 2007 Fig 1.bmp (file) 1.96 MB Junxian   1
23:46, 9 June 2007 Document2 01.png (file) 91 KB Junxian   3
23:50, 9 June 2007 Document2 05.png (file) 3 KB Junxian   2
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