Arylformamidase Function Slide 1: Difference between revisions

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== Literature Search ==
== Literature Search ==


Keyword: ''Arylformamidase'' - putative function.
'''Keyword:''' ''Arylformamidase'' - putative function.


I first did a literature search with the putative function provided with the protein accession number. The search 'arylformamidase' returned a paper describing EstE1, an arylformamidase present in the liver of Mus musculus.
'''Most-helpful Result:'''


Arylformamidase forms part of the tryptophan degradation pathway...
''Pabarcus MK, Casida JE.''
'''[http://www.ncbi.nlm.nih.gov/pubmed/15935693?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum Cloning, expression, and catalytic triad of recombinant arylformamidase.]'''
Protein Expr Purif. Nov;44(1):39-44.


[[Image:Arylformadisae_reaction.gif|centre|framed|Reaction mechanism of the mammalian arylformamidase.]]
- Describes EstE1, an arylformamidase present in the liver of ''Mus musculus''.


No evidence in this literature search suggested the existence of prokaryotic arylformamidase proteins...
'''Functional Inferences:'''
 
- Arylformamidase forms part of the tryptophan degradation pathway.
 
[[Image:Arylformadisae_reaction.gif|centre|framed|Reaction mechanism of the mammalian arylformamidase. Produced using ChemSketch.]]
 
- Secondary target of organophosphorous agents in chicken eggs (Casida, Quistad 2005).
 
- No evidence in this literature search suggested the existence of prokaryotic arylformamidase proteins.


[[Arylformamidase Function Slide 1 | ...Previous slide ]]|[[Arylformamidase| Return to the main page ]]|[[Arylformamidase Function Slide 2| Next slide... ]]
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Latest revision as of 11:48, 8 June 2008

Literature Search

Keyword: Arylformamidase - putative function.

Most-helpful Result:

Pabarcus MK, Casida JE.
Cloning, expression, and catalytic triad of recombinant arylformamidase.
Protein Expr Purif. Nov;44(1):39-44.

- Describes EstE1, an arylformamidase present in the liver of Mus musculus.

Functional Inferences:

- Arylformamidase forms part of the tryptophan degradation pathway.

Reaction mechanism of the mammalian arylformamidase. Produced using ChemSketch.

- Secondary target of organophosphorous agents in chicken eggs (Casida, Quistad 2005).

- No evidence in this literature search suggested the existence of prokaryotic arylformamidase proteins.

...Previous slide | Return to the main page | Next slide...