Arylformamidase Function Slide 2: Difference between revisions

Latest revision as of 12:19, 8 June 2008

- Screening of BLAST result (see Sebastien) for functional information.

Selected results of the BLAST search as performed by Sebastien.

- Plethora of putative assignments.

- First result with functional information available (associated literature) - Pabarcus 2006.

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 == Evidence from Similar Sequences ==
-Screening of BLAST result (see Sebastien) for associated literature.
+- Screening of BLAST result (see Sebastien) for functional information.
-Resulted in the same paper as the literature search.
+[[Image:2pblBLAST.png|centre|framed|'''Selected results of the BLAST search as performed by Sebastien.''']]
-Catalytic triad identified in paper - Ser162, Asp247, and His279.
+- Plethora of putative assignments.
-To assess functional similarity, conservation of the catalytic triad was analysed.
+- First result with functional information available (associated literature) - Pabarcus 2006.
-[[Image:arylformamidase_alignment.png|centre|framed|'''Conservation of the catalytic triad between Arylformamidase and 2pbl.''']]
-Aspartic acid --> Glutamic acid - Semi-conservative: both polar, acidic.
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