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== Function of sulfatases ==
== Function of sulfatases ==


    Sulfatases are enzymes, which hydrolyse sulfate ester bonds of substrates. Most of the family members has shown to contain a highly conserved cystine residue and a bivalent metal binding site.
Sulfatases are enzymes,which hydrolyse sulfate ester bonds of substrates.  
Most of the family members has shown to contain a highly conserved cystine residue and a bivalent metal binding site.








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== Functional site==
MSA data revealed some conserved residues on the sequence. They were mapped on the three dimantional structure.


[[Image:Zn_Cl_surface]]


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Latest revision as of 09:44, 20 May 2008

The predicted function based on the evolution and structure

Hydrolase


Document18 01.png

Hydrolyase catalyze the hydrosis of the chemical bond between A and B, resulting of 2 simple molecules


  • Hydrolase
    • Catalyze hydrolysis reaction
    • Addition of the hydrogen and hydroxyl ions of water
    • Splitting into 2 or more simpler molecules
    • EC class 3


Function of sulfatases

Sulfatases are enzymes,which hydrolyse sulfate ester bonds of substrates. Most of the family members has shown to contain a highly conserved cystine residue and a bivalent metal binding site.



Functional site

MSA data revealed some conserved residues on the sequence. They were mapped on the three dimantional structure.

File:Zn Cl surface


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