Functional analysis of 2ece
FUNCTIONAL analysis of SELENBP 1 (pdb 2ece)
DaliLite: Structural Neighbours
Query: mol1A MOLECULE: 462AA LONG HYPOTHETICAL SELENIUM-BINDING PROTEIN;
Matches are sorted by Z-score. Similarities with a Z-score lower than 2 are spurious.
Summary
No: |Chain| Z| rmsd| lali| nres| %id| Description
1: |2ece-A |80.1 |0.0 |455 |455 |100 |MOLECULE: 462AA LONG HYPOTHETICAL SELENIUM-BINDING PROTEIN; 2: |1ri6-A |32.6 |2.6 |314 |333 | 12 |MOLECULE: PUTATIVE ISOMERASE YBHE; 3: |1jof-A |31.3 |2.9 |329 |365 |10 |MOLECULE: CARBOXY-CIS,CIS-MUCONATE CYCLASE; 4: |1l0q-C |30.3 |2.2 |286 |391 | 15 |MOLECULE: SURFACE LAYER PROTEIN; 5: |1l0q-B |30.3 |2.2 |286 |391 | 15 |MOLECULE: SURFACE LAYER PROTEIN; 6: |1l0q-A |30.3 |2.2 |286 |391 | 15 |MOLECULE: SURFACE LAYER PROTEIN; 7: |1l0q-D |30.2 |2.2 |286 |391 | 15 |MOLECULE: SURFACE LAYER PROTEIN; 8: |1qni-D |28.3 |2.8 |317 |572 | 11 |MOLECULE: NITROUS-OXIDE REDUCTASE; 9: |1qni-F |28.0 |2.8 |317 |572 | 11 |MOLECULE: NITROUS-OXIDE REDUCTASE; 10: |1fwx-D |28.0 |2.8 |316 |588 | 10 |MOLECULE: NITROUS OXIDE REDUCTASE; 11: |1fwx-A |27.9 |2.9 |318 |591 |10 |MOLECULE: NITROUS OXIDE REDUCTASE; 21: |1sq9-A |25.0 |3.0 |293 |378 |10 |MOLECULE: ANTIVIRAL PROTEIN SKI8; 23: |2z2o-C |24.5 |2.6 |269 |299 |10 |MOLECULE: VIRGINIAMYCIN B LYASE; 25: |1yfq-A |24.4 |3.1 |287 |342 |11 |MOLECULE: CELL CYCLE ARREST PROTEIN BUB3; 42: |1pev-A |23.5 |2.9 |282 |610 | 9 |MOLECULE: ACTIN INTERACTING PROTEIN 1; 159: |1bpo-B |13.6 |4.1 |261 |493 | 8 |MOLECULE: CLATHRIN; 277: |1a12-B |9.3 |3.9 |235 |401 |8 |MOLECULE: REGULATOR OF CHROMOSOME CONDENSATION 1;
The above table shows some condensed Dali results. The proteins that might have direct carcinogenic effects via the immune system are highlighted. Most of the proteins that have structural similarity to SBP are highly involved in redox reactions,like the reductases.
WARNING! Given sequence appeared to be a soluble protein, no TM domains found!
Output format is the following:
1st line -> residue numeration
2nd line -> query amino acid sequence
3rd line -> trans-membrane domain prediction (T-TM region, N-soluble part)
MAIVPFKRDPTFYPSPKMAMKAPPEDLAYVACLYTGTGINRADFIAVVDVNPKSETYSKI NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN VHKVELPYINDELHHFGWNACSSALCPNGKPNIERRFLIVPGLRSSRIYIIDTKPNPREP NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KIIKVIEPEEVKKVSGYSRLHTVHCGPDAIYISALGNEEGEGPGGILMLDHYSFEPLGKW NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EIDRGDQYLAYDFWWNLPNEVLVSSEWAVPNTIEDGLKLEHLKDRYGNRIHFWDLRKRKR NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IHSLTLGEENRMALELRPLHDPTKLMGFINMVVSLKDLSSSIWLWFYEDGKWNAEKVIEI NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PAEPLEGNLPEILKPFKAVPPLVTDIDISLDDKFLYLSLWGIGEVRQYDISNPFKPVLTG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KVKLGGIFHRADHPAGHKLTGAPQMLEISRDGRRVYVTNSLYSTWDNQFYPEGLKGWMVK NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LNANPSGGLEIDKEFFVDFGEARSHQVRLSGGDASSDSYCYP NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
SABLE server results indicating that SBP is a soluble protein.Therefore, little is to be expected for it to be membrane spanning molecule, but it might be useful in the cytosol.
Back to results Results 2ece
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