Arylformamidase Function Slide 2

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Evidence from Similar Sequences

Screening of BLAST result (see Sebastien) for associated literature.

Resulted in the same paper as the literature search.

Catalytic triad identified in paper - Ser162, Asp247, and His279.

To assess functional similarity, conservation of the catalytic triad was analysed.

Conservation of the catalytic triad between Arylformamidase and 2pbl.

Aspartic acid --> Glutamic acid - Semi-conservative: both polar, acidic.

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