Arylformamidase Function Slide 7

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Identification of family.

- Byun, et al. (2007) alluded to the HSL family of lipases.

- All known structures of the HSL family of esterases (Byun, et al. 2007) are present in the DALI search.

Structures of the HSL family of esterases as identified by Byun, et al. (2007) present in the DALI results.

- 2pbl shares sequence similarity in regions characteric to the HSL family of esterases (Arpigny and Jaeger 1999).

Sequence similarity in regions characteristic to the HSL family of esterases as identified by Arpigny and Jaeger (1999).

- Characterised by their structural similarity to the mammalian hormone sensitive lipase. Surprisingly, a mammalian HSL was not returned in the BLAST search!

- 2pbl is a notably shorter peptide.


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