3bsqA Results

MSA highlited sevlral residues which are very highly conserves (figure 1).

The three dimentional structure was viewed using PyMol (figure 2)and these conserved residues were marked on the crystal structure. However they were not related to binding sited of Cl and Zn, but buried in the core of the protein within a pocket-like region(figure 3). All attempts to see the electrostatic nature of this pocket were unsuccessful, due to some technical probloems with PyMol.

Structural alignement of arylsulfatase K using DALI resulted several other sulfatases (figure 4).

Protein interactions of arylsulfatase K with other proteis were vieved usig the server STRING, which revealed four major hits, depending on XXX and XXX evidence.