Structure Protein

2ifu has 4 chains (A, B, C and D) integrated together to form the whole molecular structure as shown below:

(chain A= green, chain B= cyan, chain c= purple, and chain d= yellow)

Two molecular components were observed:

sulfate ion (SO4) and selenomethionine (MSE)

Ten sulfate ions were observed. Each ion differs in arrangement as well as orientation related with each chains.

protein sequence (FASTA)

>gi|118138356|pdb|2IFU|A Chain A, Crystal Structure Of A Gamma-Snap From Danio Rerio AIAAQKISEAHEHIAKAEKYLKTSFXKWKPDYDSAASEYAKAAVAFKNAKQLEQAKDAYLQEAEAHANNR SLFHAAKAFEQAGXXLKDLQRXPEAVQYIEKASVXYVENGTPDTAAXALDRAGKLXEPLDLSKAVHLYQQ AAAVFENEERLRQAAELIGKASRLLVRQQKFDEAAASLQKEKSXYKEXENYPTCYKKCIAQVLVQLHRAD YVAAQKCVRESYSIPGFSGSEDCAALEDLLQAYDEQDEEQLLRVCRSPLVTYXDNDYAKLAISLKVPGGG GGKKKPSASASAQPQEEEDDEYAGGLC

Strutural analysis

SNAP-GAMMA DALI

Based on Dali search, 6 proteins with highest Z-value were chosen: 1qqe-A (protein transport), 2fi7-A (protein binding), 1a17 (hydrolase), 2ak6-A, 1fch-A (signalling protein), 1haz4-A (transcription factor),

snap-gamma: multiple structure alignment

Snap-gamma: sequence alignment with 1QQE:A

Dark colors: 2ifu:A Light colors: 1qqe:A

SCOP

multiple alignment results, click here

Superimposed structure between 2ifuA; 2ifuB; 2ifuC; 2ifuD; 1qqeA; and 1b89A

ligand binding domain

electrostatic potential

electrostatic potential of proteins mapped into molecular surface. positive potentials are shown in blue while that of negative potential are in red. the electrostatic potential was calculated using Coulomb computational method.